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Doctor Karolina Janitz
Dr. Karolina Janitz is the senior technical officer responsible for the next-generation sequencing facility. Karolina came to the Hawkesbury Institute for the Environment in May 2011 from the Ramaciotti Centre for Gene Function Analysis at UNSW, where she led the Illumina next-generation sequencing platform and was pivotal in the achievement of the center’s Illumina Certified Service Provider (CSPro) status.
Karolina acquired her PhD in molecular genetics from the Freie Universität Berlin, Germany, under the supervision of Prof. Hans Lehrach from the Max Planck Institute for Molecular Genetics Berlin. Her PhD thesis focused on an investigation of the molecular mechanism of renal damage in the course of rat hypertension using laser microdissection and Affymetrix gene expression profiling.
Areas of Expertise
Karolina’s main interest and professional expertise lie in the field of next-generation sequencing. For the last two years, she has led the Illumina sequencing platform, providing outstanding, personalized customer service. She was responsible for the entire Illumina sequencing pipeline, including customer project design, consulting, sequencing data generation, and processing. Her expertise covers a broad range of Illumina’s applications, such as de novo sequencing, metagenomics, targeted resequencing using SureSelect platform, RNA-Seq (standard, directional, and normalized libraries) and epigenetic analysis (ChiP-Seq, MBD-Seq, and DNA nucleosome sequencing).
Selected Publications
Deshpande NP, Kaakoush NO, Mitchell H, Janitz K, Raftery MJ, Li SS, Wilkins MR, (2011) ‘Sequencing and Validation of the Genome of a Campylobacter concisus Reveals Intra-Species Diversity, PLoS One, vol.6, no.7, :e22170
Janitz K & Janitz M, (2011) ‘Assessing epigenetic information’, Tollefsbol, T. (ed), Handbook of Epigenetics: The New Molecular and Medical Genetics. Elsevier, pp. 173-181
Kaakoush NO, Deshpande NP, Wilkins MR, Raftery MJ, Janitz K, Mitchell H, (2011) ‘Comparative analyses of Campylobacter concisus strains reveal the genome of the reference strain BAA-1457 is not representative of the species’, Gut Pathogens, vol. 3, doi:10.1186/1757-4749-3-15
Twine NA, Janitz K, Wilkins, MR & Janitz M (2011), 'Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease', PLoS One 6: e16266
Courtney E, Kornfeld S, Janitz K, Janitz M, (2010) ‘Transcriptome profiling in neurodegenerative disease’, J Neurosci Methods 193(2):189-202
Janitz K, Twine N, Wilkins M, Janitz M, (2010) ‘Comprehensive analysis of transcriptome by means of RNA-Seq next-generation sequencing’, Australian Biochemist, vol.41, pp 18-21
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