Lukas Kairaitis

• Biography
• Areas of Research / Teaching Expertise
• Grants / Current Projects
• Awards and Recognition
• Selected Publications
• Memberships and Engagement
• Contact Details

Biography

A/Prof Lukas Kairaitis (MBBS, PhD, FRACP) is a staff specialist Nephrologist employed by Sydney West Local Health District. He also works as an academic with the University of Western Sydney and is Sub-dean of the Blacktown-Mt Druitt clinical school and the Director of Physician Training at Blacktown Hospital.

After training as a Nephrologist in Sydney he completed a PhD investigating factors involved in progressive renal damage in chronic kidney disease. He works as a consultant renal physician at Blacktown Hospital and in private practice with clinical interests in chronic kidney disease and dialysis.

He is heavily involved in the provision of undergraduate and postgraduate education to medical students from the School of Medicine at UWS and to medical registrars undertaking training for the Royal Australasian College of Physicians. He has published a number of research papers and academic texts in these areas.

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Areas of Research / Teaching Expertise

• Nephrology
• Physician Training
  

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Grants / Current Projects

NHMRC postgraduate scholarship 1999-2002 - Progressive renal damage in chronic kidney disease.

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Awards and Recognition

Consultant of the Year, Westmead Resident Medical Officers Association 2006

Best Scientific Poster
38th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Sydney 2002

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Selected Publications

Lee, VWS,Qin X, Wang Y, Zheng G, Wang Y, Wang Y, Ince J, Tan TK, Kairaitis LK, Alexander SI Harris DCH. The CD40-CD154 costimulation pathway mediates innate immune injury in adriamycin nephrosis. Nephrol Dial Transplant 2009 doi: 10.1093/ndt/gfp569

Yong KCK, Kairaitis L. Effects of proactive iron and erythropoiesis-stimulating agent protocol implementation on achieving clinical guideline targets for anaemia in a satellite haemodialysis patient cohort. Nephrology 2009 (in press)

Simon D Roger, Michael G Suranyi and Rowan G Walker on behalf of the COMFORT study group: A randomised, cross-over study comparing injection site pain with subcutaneous epoetin beta and subcutaneous darbepoetin alfa in patients with chronic kidney disease. Current Medical Research and Opinions 2008:24 (8). 2181-87

Blyth E, Favaloro EJ, Harris D, Kairaitis L. Protein Z is reduced in chronic kidney disease and not elevated in patients on haemodialysis. Blood Coag Fibrin 2007 (in press)

Kairaitis L. Prevention of recurrent calcium nephrolithiasis. Nephrology (Carlton). 2007 Feb;12 Suppl 1:S11-20.

Zheng G, Zheng L, Wang Y, Wu H, Kairaitis L, Zhang C, Tay YC, Wang Y, Alexander SI, Harris DC. NK cells do not mediate renal injury in murine adriamycin nephropathy. Kidney Int 2006 Apr;69(7):1159-65

Wang Y, Mahajan D, Tay YC, Bao S, Spicer T, Kairaitis L, Rangan G, Harris DCH. Partial depletion of macrophages by ED7 reduces renal injury in adriamycin nephropathy. Nephrology 2005; 10 (5), 470-477

Tay Y-C, Wang Y, Kairaitis L, Rangan GK, Zhang C, Harris DCH. Can murine diabetic nephropathy be separated from superimposed acute renal failure? Kidney Int 2005; 68(1): 391-8

Geevasinga N, Kairaitis L, Rangan GK, Coleman P. Acute interstitial nephritis secondary to esomeprazole. Med J Aust 2005; 182 (5): 235-6.

Kairaitis LK, Wang Y, Gassmann M, Tay Y-C, Harris DCH. HIF-1a expression follows microvascular loss in advanced murine Adriamycin nephrosis. Am J Physiol 2005; 288(1):F198-206.

Sadlier DM, Connolly SB, Kieram NE, Roxburgh S, Brazil DP, Kairaitis L, Wang Y, Harris DCH, Doran P, Brady HR. Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin induced nephropathy. J Biol Chem 2004;279(28):29670-80.

Kairaitis LK, Wang Y, Zheng L, Tay Y-C, Harris DCH. Blockade of CD40-CD40 ligand protects against renal injury in chronic proteinuric renal disease. Kidney Int 2003; 64 (4): 1265-1272.

Wang, Y-P, Yi S, Kairaitis LK, Wang Y, Rangan GK, Tay Y-C, Harris DCH. Transfection of tubule cells with Fas ligand causes leukocyte apoptosis. Kidney Int 2002, 61 (4): 1303-1311.

Chen L, Wang Y-P, Kairaitis LK, Wang Y, Zhang B-H, Harris DCH. Molecular mechanisms by which iron induces nitric oxide synthesis in cultured proximal tubule cells. Exp Nephrol 2001; 9(3): 198-204.

Wang Y-P, Wang Y, Feng X, Bao S, Yi S, Kairaitis LK, Tay Y-C, Rangan GK, Harris DCH. Depletion of CD4 (+) T cells aggravates glomerular and tubular injury in murine Adriamycin nephropathy. Kidney Int 2001; 59(3): 975-984.

Kairaitis LK, Harris DCH. Tubular interstitial interactions in proteinuric renal diseases. Nephrology 2001; 6(5): 198-213.

Kairaitis LK, Gottlieb T, George CRP. Fatal Hepatitis B virus infection with fibrosing cholestatic hepatitis following renal transplantation. Hepatitis Review Series 2000; 1:14-15

Kairaitis LK, Yuill E, Hunt C, Reid A, Liew S, Harris DCH. Determinants of haemoglobin carbamylation in haemodialysis and peritoneal dialysis patients. Nephrol Dial Transplant 2000; 15(9): 1431-7.

Kairaitis LK, Nankivell BJ, Lawrence S, Nicholl MC, O’Connell PJ, Kable K, Chapman JR, Allen RDM. Successful obstetric outcome after simultaneous pancreas and kidney transplantation. Med J Aust 1999; 170: 368-370.

Kairaitis LK, Gottlieb T. Outcome and complications of haemodialysis catheters. Nephrol Dial Transpl 1999; 14:1710-1714.

Kairaitis LK, Gottlieb T, George CRP. Fatal Hepatitis B virus infection with fibrosing cholestatic hepatitis following renal transplantation. Nephrol Dial Transplant 1998; 13: 1571-1573.

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Memberships

Royal Australasian College of Physicians
Australian and New Zealand Society of Nephrology
Kidney Health Australia (foundation member)
International Society of Nephrology
Australian Association of Consultant Physicians
American Society of Nephrology

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