I completed my undergraduate and postgraduate training at the University of New South Wales in 1992 in the area of the biosynthesis of natural products in bacteria. From late 1992-1995, I worked on fatty acid biosynthesis in bacteria and plants at the Carlsberg Laboratory, Copenhagen Denmark. In 1996-1997 I moved to the laboratory of David Cane at Brown University, Rhode Island USA, working on the polyketide synthase involved in the biosynthesis of the antibiotic erythromycin. After returning to Australia, I began working on the polyketide synthase synthesising the antifungal drug Amphotericin B in collaboration with Kevin Barrow’s research group at UNSW. I am currently working at the University of Western Sydney, (Parramatta campus) where my group is interested in the regulation and biochemistry of bioactive compounds.
Natural Products; Polyketides; Streptomyces;
Chuck, J. (2005) Characterization of the life cycle of the bacterium Streptomyces nodosus; a producer of the antibiotic amphotericin B. University of Western Sydney research grant.
Old, J. and Chuck, J. (2007) Investigation of antifungal properties of Tammar wallaby (Macropus eugenii) pouch lipid secretions. University of Western Sydney research grant.
Pereira, T., Nikodinovic J., Nakazono C., Dennis, G., Barrow K.D. and Chuck J. (2008) Sporulation and antibiotic production by planktonic and immobilized Streptomyces nodosus cultured in liquid environments. Microbial Biotechnology, 1, 373-381.
Chuck, J., Dunn, C., Nikodinovic, J., Barrow, B (2006) Amplification of DNA encoding entire type I polyketide synthase domains and linkers from Streptomyces. Current Microbiology 53, 89-94
Pereira, T., Millar, T. and Chuck, J. (2005) Viability analysis of alginate encapsulated micro-organisms using fluorescent stains. J. Microencapul. 22, 787-792 .
Chuck, J. and Young, L. (2004) A cohort driven assessment task for scientific report writing in tertiary education. J. Sci. Edu. Technol., 13, 367-376.
Nikodinovic, J., Barrow, B. and Chuck, J. (2003) A new rapid method of isolation of DNA from Streptomyces. Biotechniques 35(5):932-4
Nikodinovic, J., Barrow, B. and Chuck, J. (2003) High frequency transformation of the Amphotericin producing bacterium Streptomyces nodosus. J. Microbiol. Methods, 55, 273-277.
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