Doctor Janice Aldrich-Wright
PROFESSOR,
Dean's Unit - School of Sciences and Health
Personal
Qualifications
- PhD Macquarie University
- BAppSc NSW Institute of Technology
UWS Organisational Unit (School / Division)
- Dean's Unit - School of Sciences and Health
Contact
| Email: | J.Aldrich-Wright@uws.edu.au |
|---|---|
| Extension: | 3218 |
| Mobile: | |
| Location: | 21.G.43 Campbelltown |
| Website: |
Publications
Chapters in Books
- Van Holst, M., Grant, M. and Aldrich-Wright, J. (2011), 'Target Biological Structures: The Cell, Organelles, DNA and RNA', Metallointercalators Synthesis and Techniques to Probe Their Interactions with Biomolecules, Springer 9783211094273.
- Orkey, N., Wormell, P., Wormell, P. and Aldrich-Wright, J. (2011), 'Ruthenium Polypyridyl Metallointercalators', Metallointercalators Synthesis and Techniques to Probe Their Interactions with Biomolecules, Springer 9783211094273.
- Krause-Heuer, A., Manohar, M., Garbutcheon-Singh, K., Fisher, D. and Aldrich-Wright, J. (2011), 'The Synthesis of Platinum(II) Intercalators', Metallointercalators Synthesis and Techniques to Probe Their Interactions with Biomolecules, Springer 9783211094273.
- Harper, B., Van Holst, M. and Aldrich-Wright, J. (2011), 'Platinum(II) Intercalating Complexes Based on 2,2':6',2"-Terpyridine', Metallointercalators Synthesis and Techniques to Probe Their Interactions with Biomolecules, Springer 9783211094273.
- Salih, A., Wormell, P., Garbutcheon-Singh, K., Harper, B., Myers, S., Geny, D., Hammang, C. and Aldrich-Wright, J. (2011), 'Applications of Fluorescence Spectroscopy and Confocal Microscopy.', Metallointercalators Synthesis and Techniques to Probe Their Interactions with Biomolecules, Springer 9783211094273.
Journal Articles
- Leverett, P., Wu, M. and Aldrich-Wright, J. (2013), 'The antimicrobial properties of some copper(II) and platinum(II) 1,10-phenanthroline complexes', Dalton Transactions, 14.
- Wang, S., Higgins, V., Aldrich-Wright, J. and Wu, M. (2012), 'Identification of the molecular mechanisms underlying the cytotoxic action of a potent platinum metallointercalator', Journal of Chemical Biology, 11.
- Krause-Heuer, A., Price, W. and Aldrich-Wright, J. (2012), 'Spectroscopic investigations on the interactions of potent platinum(II) anticancer agents with bovine serum albumin', Journal of Chemical Biology, 9.
- Davis, K., Carral, J., Lai, B., Aldrich-Wright, J., Ralph, S. and Dillion, C. (2012), 'Does Cytotoxicity of Metallointercalators Correlate with Cellular Uptake or DNA Affinity?', Dalton Transactions, 10.
- Wang, S., Higgins, V., Wu, M. and Aldrich-Wright, J. (2012), 'Comparative analyses of cytotoxicity and molecular mechanisms between novel platinum metallointercalators and cisplatin', Metallomics, 10.
- Orkey, N., Taleb, R. and Aldrich-Wright, J. (2012), 'Synthesis and Characterisation of Metallopolyamide Complexes', Inorganica Chimica Acta, 11.
- Krause-Heuer, A., Bolhuis, A. and Aldrich-Wright, J. (2012), 'Copper(II) and palladium(II) complexes with cytotoxic and antibacterial activity', Australian Journal of Chemistry, 14.
- Aldrich-Wright, J. (2012), 'Metallo-Helical Complexes resolutely pure helices', Nature Chemistry, 2.
- Orkey, N., Taleb, R. and Aldrich-Wright, J. (2012), 'Synthesis and characterisation of metallopolyamide complexes', Inorganica Chimica Acta, 11.
- Krause-Heuer, A., Price, W. and Aldrich-Wright, J. (2012), 'Spectroscopic investigations on the interactions of potent platinum(II) anticancer agents with bovine serum albumin', Journal of Chemical Biology, 9.
- Davis, K., Carrall, J., Lai, B., Aldrich-Wright, J., Ralph, S. and Dillon, C. (2012), 'Does cytotoxicity of metallointercalators correlate with cellular uptake or DNA affinity?', Dalton Transactions, 10.
- Krause-Heuer, A., Leverett, P., Bolhuis, A. and Aldrich-Wright, J. (2012), 'Copper(ii) and palladium(ii) complexes with cytotoxic and antibacterial activity', Australian Journal of Chemistry, 14.
- Wang, S., Wu, M., Wu, M., Higgins, V. and Aldrich-Wright, J. (2012), 'Comparative analyses of cytotoxicity and molecular mechanisms between platinum metallointercalators and cisplatin', Metallomics, 10.
- Wang, S., Higgins, V., Aldrich-Wright, J., Aldrich-Wright, J., Wu, M. and Wu, M. (2012), 'Identification of the molecular mechanisms underlying the cytotoxic action of a potent platinum metallointercalator', Journal of Chemical Biology, 11.
- Aldrich-Wright, J. (2012), 'Metallo-helical complexes resolutely pure helices', Nature Chemistry, 2.
- Moretto, J., Chauffert, B., Ghiringhelli, F., Aldrich-Wright, J. and Bouyer, F. (2011), 'Discrepancy between in vitro and in vivo antitumor effect of a new platinum (II) Metallointercalator', Investigational New Drugs, 13.
- Garbutcheon-Singh, K., Grant, M., Harper, B., Manohar, M., Krause-Heuer, A., Orkey, N. and Aldrich-Wright, J. (2011), 'Transition metal based anticancer drugs', Current Topics in Medicinal Chemistry, 22.
- Bolhuis, A., Hand, L., Marshall, J., Richards, A., Rodger, A. and Aldrich-Wright, J. (2011), 'Antimicrobial activity of ruthenium-based intercalators', European Journal of Pharmaceutical Sciences, 5.
- Harper, B., Krause-Heuer, A., Grant, M., Manohar, M., Garbutcheon-Singh, K. and Aldrich-Wright, J. (2010), 'Advances in platinum chemotherapeutics', Chemistry : A European Journal, 14.
- Talib, J., Harman, D., Dillon, C., Aldrich-Wright, J., Beck, J. and Ralph, S. (2009), 'Does the metal influence non-covalent binding of complexes to DNA', Dalton Transactions, 10.
- Grant, M., Wheate, N. and Aldrich-Wright, J. (2009), 'Diffusion Coefficient of Curcurbit[n]urils (n=6 or 7) at Various Concentrations, Temperature and pH', Journal of Chemical & Engineering Data, 4.
- Pisani, M., Wheate, N., Keene, F., Aldrich-Wright, J. and Collins, J. (2009), 'Anionic PAMAM dendrimers as drug delivery vehicles for transition metal-based anticancer drugs', Journal of Inorganic Biochemistry, 8.
- Jones, D., Van Host, M., Yano, S., Tanase, T. and Aldrich-Wright, J. (2009), 'N-Glycoside Complexes of Nickel(II); Probing Carbohydrate-Transition Metal Interactions', Australian Journal of Chemistry, 4.
- Krause-Heuer, A., Wheate, N., Price, W. and Aldrich-Wright, J. (2009), 'Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators', Chemical Communications, 3.
- Krause-Heuer, A., Malina, J., Bednarski, P., Brabec, V., Aldrich-Wright, J., Grnert, R., Khne, S., Buczkowska, M., Wheate, N., Le Pevelen, D., Boag, L., Fisher, D. and Kasparkova, J. (2009), 'Studies of the Mechanism of Action of Platinum (II) complexes with Potent Cytotoxicity in Human Cander Cells', Journal of Medicinal Chemistry, 11.
- Talib, J., Beck, J., Urathamakul, T., Nguyen, C., Aldrich-Wright, J., Mackay, J. and Ralph, S. (2009), 'A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity', Chemical Communications, 3.
- Amon, M., Ali, M., Bender, V., Hall, K., Aguilar, M., Aldrich-Wright, J. and Manolios, N. (2008), 'Kinetic and conformational properties of a novel T-cell antigen receptor transmembrane peptide in model membranes', Journal of Peptide Science, 11.
- Urathamakul, T., Waller, D., Beck, J., Aldrich-Wright, J. and Ralph, S. (2008), 'Comparison of Mass Spectrometry and Other Techniques for Probing Interactions Between Metal Complexes and DNA', Inorganic Chemistry, 12.
- Krause-Heuer, A., Wheate, N., Tilby, M., Pearson, G., Ottley, C. and Aldrich-Wright, J. (2008), 'Substituted B Cyclodextrin and Calix[4]arene as Encapsulatory Vehicles for Platinum(II)-Based DNA Intercalators', Inorganic Chemistry, 9.
- Kemp, S., Wheate, N., Pisani, M. and Aldrich-Wright, J. (2008), 'Degredation of Bidentate-Coordinated Platinum(II) Based DNA Intercalators by Reduced L-Glutathione', Journal of Medicinal Chemistry, 8.
- Wheate, N., Payyadi Govardhan, A., Torres, A., Aldrich-Wright, J. and Price, W. (2008), 'Examination of cucurbit[7]uril and its host-guest complexes by diffusion nuclear magnetic resonance', Journal of Physical Chemistry B, 4.
- Talib, J., Green, C., Davis, K., Beck, J., Urathamakul, T., Aldrich-Wright, J. and Ralph, S. (2008), 'A comparison of the binding of metal complexes to duplex and quadruplex DNA', Journal of the Chemical Society, Dalton Transactions, 9.
- Van Holst, M., Le Pevelen, D. and Aldrich-Wright, J. (2008), 'Terpyridineplatinum (II) Incorporation in N-Methylpyrrole-Based Polyamides by Solid Phase Techniques', European Journal of Inorganic Chemistry, 8.
- Krause-Heuer, A., Grant, M., Orkey, N. and Aldrich-Wright, J. (2008), 'Drug Delivery Devices and Targeting Agents for Platinum (II) Anticancer Complexes', Australian Journal of Chemistry, 7.
- Fisher, D., Fenton, R. and Aldrich-Wright, J. (2008), 'In vivo studies of platinum (II) metallointercalators', Chemical Communications, 3.
- Yousouf, S., Brodie, C., Wheate, N. and Aldrich-Wright, J. (2007), 'Synthesis of a heterodinuclear ruthenium(II)-platinum(II) complex linked by L-cysteine methyl ester', Polyhedron, 11.
- Still, B., Payyadi Govardhan, A., Aldrich-Wright, J. and Price, W. (2007), '195Pt NMR-theory and application', Chemical Society Reviews, 22.
- Taleb, R., Jaramillo, D., Wheate, N. and Aldrich-Wright, J. (2007), 'Synthesis of DNA-sequence-selective hairpin polyamide platinum complexes', Chemistry: A European Journal, 10.
- Fisher, D., Bednarski, P., Grunert, R., Turner, P., Fenton, R. and Aldrich-Wright, J. (2007), 'Chiral platinum(II) metallointercalators with potent in vitro cytotoxic activity', ChemMedChem, 8.
- Wheate, N., Brodie, C., Collins, G., Kemp, S. and Aldrich-Wright, J. (2007), 'DNA intercalators in cancer therapy: Organic and inorganic drugs and their spectroscopic tools of analysis', Mini Reviews in Medicinal Chemistry, 22.
- Kemp, S., Wheate, N., Buck, D., Nikac, M., Collins, J. and Aldrich-Wright, J. (2007), 'The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators', Journal of Inorganic Biochemistry, 10.
- Aldrich-Wright, J., Fenton, R., Leverett, P., Stephens, F., Williams, P. and Vagg, R. (2007), 'The synthesis and structural analysis of cis-beta-{(1,6-di(2'-pyridyl)(2,5-dibenzyl-2,5-diazahexane)(1,2-diazahexane)(1,2-benzoquinone diimine)ruthenium(II)} and related complexes', Journal of Coordination Chemistry, 20.
- Kemp, S., Wheate, N., Stootman, F. and Aldrich-Wright, J. (2007), 'The host-guest chemistry of proflavine with cucurbit[6,7,8]urils', Supramolecular Chemistry, 10.
- Wheate, N., Taleb, R., Krause-Heuer, A., Cook, R., Higgins, V., Aldrich-Wright, J. and Wang, S. (2007), 'Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles', Journal of the Chemical Society, Dalton Transactions, 10.
- Brodie, C. and Aldrich-Wright, J. (2007), 'Synthesis of Flexible Bis-Intercalating Ruthenium (II) Complexes', European Journal of Inorganic Chemistry, 13.
- Kemp, S., Wheate, N., Wang, S., Collins, G., Higgins, V., Aldrich-Wright, J., Ralph, S. and Day, A. (2007), 'Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils', Journal of Biological Inorganic Chemistry, 11.
- Jaramillo, D., Junk, P., Brodie, C. and Aldrich-Wright, J. (2006), 'chloro(dimehtylsulfoxide-kS)[(1R,3S)-1,2,2-trimethylcyclopentane-1,3-diamine-k2N,N']platinum(II) trichloro(dimethyl sulfoxide-kS)platinum(II)', Acta Crystallographica E, 3.
- Stootman, F., Fisher, D., Rodger, A. and Aldrich-Wright, J. (2006), 'Improved curve fitting procedures to determine equilibrium binding constants', The Analyst, 7.
- Brodie, C., Turner, P., Wheate, N. and Aldrich-Wright, J. (2006), '(4,7-dimethyl-1,10-phenanthroline)ethylenediamine)platinum(II) dichloride tris(deuterium oxide) solvate', Acta Crystallographica. Section E: Structure Reports Online, 3.
- Jaramillo, D., Buck, D., Collins, J., Wheate, N., Stootman, F., Aldrich-Wright, J. and Fenton, R. (2006), 'Synthesis, characterisation and biological activity of chiral platinum(II) complexes', European Journal of Inorganic Chemistry, 11.
- Jaramillo, D., Wheate, N., Ralph, S., Howard, W., Tor, Y. and Aldrich-Wright, J. (2006), 'Polyamide platinum anticancer complexes designed to target specific DNA sequences', Inorganic Chemistry, 10.
- Jaramillo, D., Liu, Q., Aldrich-Wright, J. and Yitzhak, T. (2004), 'Synthesis of N-Methylpyrrole and N-Methylimidaqzole Amino Acids Suitable for Solid-Phase Synthesis', Journal of Organic Chemistry, 3.
- Brodie, C., Collins, J. and Aldrich-Wright, J. (2004), 'DNA binding and biological activity of some platinum(II) intercalating compounds containing methyl-substituted 1,10-phenanthrolines', Dalton Transactions, 8.
- Urathamakul, T., Beck, J., Sheil, M., Aldrich-Wright, J. and Ralph, S. (2004), 'A mass spectrometric investigation of non-covalent interactions between ruthenium complexes and DNA', Dalton Transactions, 8.
- Gupta, R., Beck, J., Ralph, S., Sheil, M. and Aldrich-Wright, J. (2004), 'Comparison of the Binding Stoichiometries of Positively Charged DNA-Binding Drugs using positive and negative ion electrospray ionization mass spectrometry', American Society for Mass Spectronomy Journal, 10.
- Aldrich-Wright, J., Brodie, C., Glazer, E., Luedtke, N., Elson-Schwab, L. and Tor, Y. (2004), 'Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+', Chemical Communications, 2.
- Pellegrini, P. and Aldrich-Wright, J. (2003), 'Evidence for chiral discrimination of ruthenium(II) polypyridyl complexes by DNA', Dalton Transactions, 8.
- Aldrich-Wright, J., Vagg, J. and Williams, P. (2003), 'HPLC separation of diasteromeric metal complexes of the form Delta, Lambda-[Ru(diimine)2(S-aminoacidate)].', Australian Journal of Chemistry, 8.
- Aldrich-Wright, J. and Howard, W. (2003), 'DNA binding studies of ruthenium (II) dipyridotetrahydrophenazine complexes', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Jaramillo, D., Collins, G. and Junk, P. (2003), 'The structure-Activity relationship of Chiral Square-Planar Platinum(II) Metallointercalators', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Ralph, S., Gupta, R., Urathamakul, T., Sheil, M. and Beck, J. (2003), 'Probing the DNA selectivity of Ruthenium Metallointercalators usin ESI Mass Spectometry', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Yousouf, S. and Brodie, C. (2003), 'Synthesis of Ruthenuym-Platinum Di- and Tri- nuclear Complexes', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Collins, G. and Keene, R. (2003), 'Dinuclear Ruthenium Complexes as Sequence- and Structure-Selective binding agents for DNA', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Brodie, C., Glazer, E., Luedtke, N. and Tor, Y. (2003), 'Synthesis and DNA binding of bisintercalating complexes of the type [(dpq)(2)Ru(phen-n-SOS-n-phen)Ru(dpq)(2)](4+)', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Fenton, R. and Fisher, D. (2003), 'Platinum(II) Intercalators as potential Anti-Cancer Agents', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Hinds, F., Leverett, P. and Hazell, S. (2003), 'Synthesis, characterisation and anti bacterial testing of Bismuth maltol', Journal of Inorganic Biochemistry, 1.
- Aldrich-Wright, J., Van Holst, M. and Jaramillo, D. (2003), 'The Synthesis of 2,3-Diamino-2,3-dideoxy-a-D-glucose, 3,4-Diamino-6-hydroxymethyl-tetrahydro-pyran-2,5-diol and their Chiral Platinum Compounds', Journal of Inorganic Biochemistry, 1.
- Back, J., Gupta, R., Urathamakul, T., Williamson, N., Sheil, M., Aldrich-Wright, J. and Ralph, S. (2003), 'Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry', Chemical Communications, 2.
- Greguric, A., Greguric, I., Hambley, T., Aldrich-Wright, J. and Collins, G. (2002), 'Minor Groove Intercalation of D-[Ru(Me2phen)2dppz]2+ to the Hexanucleotide d(GTCGAC)2', Journal of the Chemical Society, Dalton Transactions, 7.
- Hinds, F., Harris, A., Campbell, M., Aldrich-Wright, J. and Hazell, S. (2002), 'Iron transport systems are necessary to Helicobacter pylori, providing a level of protection against bismuth activity.', Gut, .
- Aldrich-Wright, J., Fenton, R., Greguric, I., Hambley, T. and Williams, P. (2002), 'The stereospecific synthesis of Lambda-alpha-{dipyrido[3,2-a:2'3'-c](6,7,8,9-tetrahydro)phenazine[N,N'-di(2-picolyl)-2,5-dimethyl-2S,5S-diaminocyclohexane]ruthenium(II)} and related beta isomers', Journal of the Chemical Society, Dalton Transactions, 6.
Conference Papers
- Aldrich-Wright, J., Wheate, N. and Taleb, R. (2007), 'Novel platinum(II) based anticancer drugs; metallointercalators and DNA sequence specific agents', 13th International Conference on Biological Inorganic Chemistry, Vienna, Austria.
- Aldrich-Wright, J., Wheate, N., Wright, E., Dawes, I. and Higgins, V. (2007), 'Molecular mechanisms involved in the Saccharomyces cerevisiae response to the novel anticance platinum compond 56MESS', 13th International Conference on Biological Inorganic Chemistry, Vienna, Austria.
- Aldrich-Wright, J., Wheate, N. and Krause-Heuer, A. (2007), 'Use of molecular hosts in the drug delivery of platinum(II) based DNA intercalating agents', 13th International Conference on Biological Inorganic Chemistry, Vienna, Austria.
- Wang, S., Cook, R., Aldrich-Wright, J. and Higgins, V. (2007), 'Structural-cytotoxicity relationships of nevel platinum anticance drugs in cancer cells and Saccaromyces cerevisiae', XXIIIrd International Conference of Yeast Genetics and Molecular Biology, Melbourne, Australia.
- Wright, E., Aldrich-Wright, J., Wheate, N., Dawes, I. and Higgins, V. (2007), 'The use of a Saccharomyces cerevisiae deletion mutant library to elucidate the molecular mechanisms involved in the eukaryote response to the novel platinum anticancer compound 56MESS', XXIIIrd International Conference of Yeast Genetics and Molecular Biology, Melbourne, Australia.
- Miyoshi, E., Price, W. and Aldrich-Wright, J. (2005), 'Multinuclear NMR and in vivo studies of platinum-based anti-cancer drugs.', College of Science, Technology and Environment Innovation Conference 2005, Werrington South, NSW, Australia.
- Apps, M., Price, W. and Aldrich-Wright, J. (2005), 'NMR and optical studies of the association of biomolecules', College of Science, Technology and Environment Innovation Conference 2005, Werrington South, NSW, Australia.
Other Publications
- 2002, '', Patent
- 2002, '', Patent
Research
Current Projects
| Title: | SRCD study of copper metallointercalators and their effect on biomacromolecule |
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| Years: | 2013-09-16 - 2013-09-22 |
| ID: | P00021287 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Spin - Switch Materials in Molecular Recognition: towards Molecular devices |
| Years: | 2012-11-13 - 2013-11-12 |
| ID: | P00021171 |
| UWS Researchers: | Feng Li and Janice Aldrich-Wright |
| Funding: |
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| Title: | Designing multidentate ligands for lanthanide complexes for the visualization of cellular components |
| Years: | 2012-03-02 - 2013-07-31 |
| ID: | P00020540 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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Previous Projects
| Title: | Sequence selective platinum drugs for DNA |
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| Years: | 2004-02-16 - 2005-02-15 |
| ID: | P0011764 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | The Synthesis of Bis-intercalating Metal Complexes with Sequence-Specific Recognition in the Minor Groove of DNA |
| Years: | 2001-01-01 - 2001-12-31 |
| ID: | P0011868 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | The Biological Evaluation of Bis-intercalating Metal Complexes |
| Years: | 2002-01-01 - 2002-12-31 |
| ID: | P0011534 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | The Synthesis of Sequence-Selective Platinum Drugs |
| Years: | 2003-01-04 - 2004-01-31 |
| ID: | P0011686 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Newbio Pre-establishment Project |
| Years: | 2005-03-01 - 2006-03-01 |
| ID: | P0014710 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Vibrational Spectroscopy /Microprobe/FESEM/AFM Imaging Cells, Tissues and Materials [via USYD] |
| Years: | 2005-04-04 - 2006-04-04 |
| ID: | P0014725 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Anti Cancer - Intercalating Metal Complexes (Project 2) |
| Years: | 2005-05-10 - 2007-06-30 |
| ID: | P0014745 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Anti Cancer - Sequence Selective Compounds (Project 3) |
| Years: | 2005-05-11 - 2007-06-30 |
| ID: | P0014746 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Platinum (II) Anticancer Drugs |
| Years: | 2005-12-21 - 2006-02-28 |
| ID: | P0014990 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Investigations into Metallodrugs Mechanisms of Action |
| Years: | 2007-06-05 - 2008-06-04 |
| ID: | P0015647 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Developing comprehensive methods for bimolecular analysis using NMR, Circular Dichroism (CD) and Linear Dichroism (LD) to understand of the mechanisms of intermolecular interactions |
| Years: | 2007-08-06 - 2012-09-30 |
| ID: | P0015753 |
| UWS Researchers: | Janice Aldrich-Wright and Bill Price |
| Funding: |
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| Title: | Are Linked Bisintercalating Platinum (II) Compounds Effective as Anticancer Agents? |
| Years: | 2007-12-10 - 2008-12-09 |
| ID: | P0015919 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Using Circular and Linear Dichromism to Understand the Binding Interactions of Platinum (II) Intercalculators with Biomolecules |
| Years: | 2006-06-08 - 2007-06-07 |
| ID: | P0015163 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Programmable Peltier Temperature Controller |
| Years: | 2006-11-15 - 2006-12-31 |
| ID: | P0015270 |
| UWS Researchers: | Janice Aldrich-Wright, Bill Price, Vincent Higgins and Frank Stootman |
| Funding: |
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| Title: | Anionic dendrimers for improved delivery of platinum anticancer drugs |
| Years: | 2006-12-20 - 2008-01-03 |
| ID: | P0015411 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | COST Action CM1105 Management Committee Meeting and Whole Action Meeting |
| Years: | 2012-09-12 - 2012-09-25 |
| ID: | P00021139 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Quality assurance and bioavailability of a Chinese herbal proprietary formula |
| Years: | 2002-12-16 - 2004-03-31 |
| ID: | P0010628 |
| UWS Researchers: | Alan Bensoussan, Cheang Khoo, Janice Aldrich-Wright, Andrew Shalliker, Kamali Kannangara, Dennis Chang and Mick Wilson |
| Funding: |
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| Title: | Isolation and Characterisation of individual components of complex organic mixtures using Liquid Chromatography-Mass Spectrometry (LC-MS/MS) |
| Years: | 2005-10-05 - 2006-10-04 |
| ID: | P0014808 |
| UWS Researchers: | Kamali Kannangara, Andrew Shalliker and Janice Aldrich-Wright |
| Funding: |
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| Title: | Dinuclear Ruthenium Complexes as Sequence- and Structure-Selective Binding Agents for DNA - DP0343480 [via James Cook University] |
| Years: | 2003-01-01 - 2005-12-31 |
| ID: | P0009800 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Circular Dichroism - Measuring molecular interactions and dynamics in biological chemistry [via Macquarie Uni]- RIEF: R00107905 |
| Years: | 2001-01-01 - 2001-12-31 |
| ID: | P0013590 |
| UWS Researchers: | Janice Aldrich-Wright, Stuart Hazell and Jo-Anne Chuck |
| Funding: |
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| Title: | Electrochemical Electron Spin Resonance Spectrometer [via University of Wollongong] |
| Years: | 2004-01-01 - 2004-12-31 |
| ID: | P0013600 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | The Selective DNA Binding of Chrial Metal Complexes |
| Years: | 1998-01-01 - 1998-12-31 |
| ID: | P0011170 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | The Synthesis and Characterisation of Carbohydrate-Metal Complexes for Interaction with DNA |
| Years: | 1999-01-01 - 1999-12-31 |
| ID: | P0011176 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Synthsesis and Resolution of Chiral Metal Complexes for Selective DNA Binding |
| Years: | 1999-01-01 - 1999-12-31 |
| ID: | P0011180 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Chiral Metal Complexes |
| Years: | 2000-01-01 - 2001-12-31 |
| ID: | P0011192 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Design and Synthesis of Dinuclear Metal Complexes with Sequences-Specific Recognition in the DNA Minor Grove |
| Years: | 2000-01-01 - 2000-12-31 |
| ID: | P0011212 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | Purchase of protein Synthesiser for Sequence Selective Drug Design |
| Years: | 2004-07-15 - 2005-07-14 |
| ID: | P0014391 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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| Title: | A PFG indirect detection nano probe for the spectroscopy of bioactive molecules |
| Years: | 2000-01-01 - 2000-12-31 |
| ID: | P0012786 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | A PFG indirect nano probe for the spectroscopy of bioactive molecules |
| Years: | 1999-11-16 - 2001-12-31 |
| ID: | P0012790 |
| UWS Researchers: | Janice Aldrich-Wright and Mark Williams |
| Funding: |
|
| Title: | Mathematical modelling of biomolecular association processes at the Nanoscale |
| Years: | 2004-09-06 - 2005-09-05 |
| ID: | P0013684 |
| UWS Researchers: | Bill Price and Janice Aldrich-Wright |
| Funding: |
|
| Title: | Characterisation and commercialisation of Bioactives in medical mushrooms |
| Years: | 2005-01-01 - 2007-12-31 |
| ID: | P0014445 |
| UWS Researchers: | John Cairney, Mick Wilson, Kai Yip Cho, Kamali Kannangara, Gary Dennis and Janice Aldrich-Wright |
| Funding: |
|
| Title: | Characterisation and commercialisation of bioactives in medical mushrooms |
| Years: | 2004-06-21 - 2007-06-20 |
| ID: | P0011412 |
| UWS Researchers: | Mick Wilson, Kai Yip Cho, Kamali Kannangara, Gary Dennis and Janice Aldrich-Wright |
| Funding: |
|
| Title: | Ultra-High Resolution NMR Imaging System for Nanotechnology including Nanobiotechnology |
| Years: | 2005-01-19 - 2006-06-06 |
| ID: | P0014448 |
| UWS Researchers: | Bill Price, Mick Wilson, Jann Conroy, Peter Williams, Andrew Shalliker, Janice Aldrich-Wright and Kamali Kannangara |
| Funding: |
|
| Title: | Effectively Targeting Anticancer Agents |
| Years: | 2008-12-18 - 2009-12-17 |
| ID: | P00016471 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | CD DNA binding of platinum (II) intercalating compounds [no funding to UWS] |
| Years: | 2009-07-12 - 2009-07-17 |
| ID: | P00016709 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | Cell and Protein Analysis Unit |
| Years: | 2009-09-22 - 2010-09-21 |
| ID: | P00017371 |
| UWS Researchers: | Simon Myers, Jens Coorssen, Jens Coorssen, Sabine Piller, Annemarie Hennessy, Janice Aldrich-Wright, Soon Lee and Gerald Muench |
| Funding: |
|
| Title: | Designing Effective Metallodrugs |
| Years: | 2009-10-28 - 2010-10-27 |
| ID: | P00017592 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | Fluorescent and Sequence Selective DNA Antibacterial Agents |
| Years: | 2009-12-04 - 2010-12-03 |
| ID: | P00017715 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | Metallointercalators as Anticancer and Antibacterial Agents |
| Years: | 2008-10-01 - 2012-03-31 |
| ID: | P00016174 |
| UWS Researchers: | Janice Aldrich-Wright, Bill Price and Vincent Higgins |
| Funding: |
|
| Title: | Novel Spectroscopic Techniques for The Investigation of Membrane Drug Interactions |
| Years: | 2010-05-28 - 2011-05-27 |
| ID: | P00018715 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | CD DNA binding of platinum (II) intercalating compounds |
| Years: | 2009-06-25 - 2009-07-17 |
| ID: | P00016949 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | CD DNA binding of platinum (II) intercalating compounds |
| Years: | 2009-07-13 - 2009-07-19 |
| ID: | P00016950 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | Synchrotron CD Study of a alpha-synuclein in the presence of metal complexes |
| Years: | 2010-07-01 - 2010-07-04 |
| ID: | P00018147 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | The role of redox balance and reactive oxygen species in beer stability using an integrated transcriptomic and metabolomic analysis |
| Years: | 2007-07-03 - 2011-09-30 |
| ID: | P0015191 |
| UWS Researchers: | Vincent Higgins and Janice Aldrich-Wright |
| Funding: |
|
| Title: | Metallointercalator Antibacterial Agents |
| Years: | 2010-11-30 - 2012-02-29 |
| ID: | P00019675 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | Cost D39 - Non-covalent metallo-drugs working group 2 |
| Years: | 2011-06-24 - 2011-07-22 |
| ID: | P00020030 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | SRCD study of quadruplex DNA and induced effects of metal complexes |
| Years: | 2012-06-25 - 2012-07-01 |
| ID: | P00020751 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | Branched degradable polymers for anti-cancer drugs delivery |
| Years: | 2011-11-09 - 2012-11-08 |
| ID: | P00020491 |
| UWS Researchers: | Patrice Castignolles, Janice Aldrich-Wright and Mark Jones |
| Funding: |
|
| Title: | Cost D39 - Non-covalent metallo-drugs working group 2 - Undertake research at Birmingham University and participate in a Circular and Linear Dichroism workshop at the University of Warwick [via Australian Academy of Science] |
| Years: | 2011-11-21 - 2011-12-16 |
| ID: | P00020468 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
|
| Title: | Synchrotron CD Study of proteins and quadraplex DNA in the presence of metal complexes (no funding to UWS) |
| Years: | 2011-06-29 - 2011-07-15 |
| ID: | P00020064 |
| UWS Researchers: | Janice Aldrich-Wright |
| Funding: |
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