
Doctor Michelle Moffitt
SENIOR LECTURER,
Medical Science (SoSH)
Personal
Qualifications
- PhD University of New South Wales
- BSc University of New South Wales
UWS Organisational Unit (School / Division)
- Medical Science (SoSH)
Contact
| Email: | M.Moffitt@uws.edu.au |
|---|---|
| Extension: | 3521 |
| Mobile: | |
| Location: | 21.1.06 Campbelltown |
| Website: |
PLEASE NOTE: obtaining information from this Directory must be for the legitimate purposes of doing business with and within the University of Western Sydney (UWS), and must not be used for unsolicited bulk e-mailing (spamming) or similar purposes.
Publications
Chapters in Books
- Neilan, B., Pearson, L., Moffitt, M., Kaebernick, M., Mihali, T. and Kellmann, R. (2008), 'The genetics and genomics of cyanobacterial toxicity', Cyanobacterial harmful Algal Blooms: State of the Science and Research Needs, Springer New York 9780387758640.
Journal Articles
- Cronin, L., Moffitt, M., Mawad, D., Morton, O., Lauto, A. and Stack, C. (2013), 'An in vitro study of the photodynamic effect of rose bengal on Trichophyton rubrum.', Journal of Biophotonics, .
- Moffitt, M. (2013), 'Environmental conditions that influence toxin biosynthesis in cyanobacteria', Environmental Microbiology, 15.
- Gehringer, M., Adler, L., Roberts, A., Moffitt, M., Mihali, T., Mills, T., Fieker, C. and Neilan, B. (2012), 'Nodularin, a cyanobacterial toxin, is synthesized in planta by symbiotic Nostoc sp.', ISME journal, 14.
- Pearson, L., Mihali, T., Moffitt, M., Kellmann, R. and Neilan, B. (2010), 'On the Chemistry, Toxicology and Genetics of the Cyanobacterial Toxins, Microcystin, Nodularin, Saxitoxin and Cylindrospermopsin', Marine Drugs, 31.
- Wiese, M., D'Agostino, P., Mihali, T., Moffitt, M. and Neilan, B. (2010), 'Neurotoxic alkaloids: saxitoxin and its analogs', Marine Drugs, 27.
- Pearson, L., Moffitt, M., Ginn, H. and Neilan, B. (2008), 'The molecular genetics and regulation of cyanobacterial peptide hepatotoxin biosynthesis', Critical Reviews in Toxicology, 10.
- Winter, J., Moffitt, M., Zazopoulos, E., Mcalpine, J., Dorrestein, P. and Moore, B. (2007), 'Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster', Journal of Biological Chemistry, 7.
- Moffitt, M., Louie, G., Bowman, M., Pence, J., Noel, J. and Moore, B. (2007), 'Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization.', Biochemistry-US, 9.
- Hicks, L., Moffitt, M., Beer, L., Moore, B. and Kelleher, N. (2006), 'Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase', A C S Chemical Biology, 10.
- Louie, G., Bowman, M., Moffitt, M., Baiga, T., Moore, B. and Noel, J. (2006), 'Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases', Chemistry and Biology, 12.
- Burns, B., Saker, M., Moffitt, M. and Neilan, B. (2004), 'Molecular detection of genes responsible for cyanobacterial toxin production in the genera Microcystis, Nodularia, and Cylindrospermopsis', Methods in Molecular Biology, 10.
- Pomati, F., Moffitt, M., Cavaliere, R. and Neilan, B. (2004), 'Evidence for differences in the metabolism of saxitoxin and C1+2 toxins in the freshwater cyanobacterium Cylindrospermopsis raciborskii T3', Biochimica et Biophysica Acta - General subjects, 8.
- Toh, M., Moffitt, M., Henrichsen, L., Raferty, M., Barrow, K., Cox, J., Marquis, C. and Neilan, B. (2004), 'Cereulide, the emetic toxin of Bacillus cereus, is putatively a product of nonribosomal peptide synthesis', Journal of Applied Microbiology, 9.
- Moffitt, M. and Neilan, B. (2004), 'Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins', Applied and Environmental Microbiology, 10.
- Moffitt, M. and Neilan, B. (2003), 'Evolutionary affiliations within the superfamily of ketosynthases reflect complex pathway associations', Journal of Molecular Evolution, 12.
- Feitz, A., Lukondeh, T., Moffitt, M., Burns, B., Naidoo, D., Della Vedova, J., Gooden, J. and Neilan, B. (2002), 'Absence of detectable levels of the cyanobacterial toxin (microcystin-LR) carry-over into milk', Toxicon, 8.
- Moffitt, M., Blackburn, S. and Neilan, B. (2001), 'rRNA sequences reflect the ecophysiology and define the toxic cyanobacteria of the genus Nodularia', International Journal of Systematic and Evolutionary Microbiology, 8.
- Moffitt, M. and Neilan, B. (2001), 'On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia', FEMS Microbiology Letters, 8.
Research
Previous Projects
| Title: | Natural product genes in cyanobacteria: From microbial genetics to biotechnological applications |
|---|---|
| Years: | 2007-12-10 - 2009-06-30 |
| ID: | P0015934 |
| UWS Researchers: | Michelle Moffitt |
| Funding: |
|
| Title: | Characterising Genes For The Biosynthesis Of Isoprenoid-Isonitrile Alkaloids In Microorganisms |
| Years: | 2006-09-30 - 2007-11-15 |
| ID: | P0015261 |
| UWS Researchers: | Michelle Moffitt |
| Funding: |
|
| Title: | Polyketides as the conserved basis for diverse marine toxin biosyntheses [via UNSW] |
| Years: | 2008-02-11 - 2011-02-10 |
| ID: | P0015529 |
| UWS Researchers: | Michelle Moffitt |
| Funding: |
|
| Title: | Establishment of a mass spectrometer facility for natural products and proteomics research and teaching at the College of Health and Science within the University of Western Sydney, Campbelltown campus |
| Years: | 2008-09-24 - 2010-09-15 |
| ID: | P00016326 |
| UWS Researchers: | Nikolaus Sucher, Jens Coorssen, Jens Coorssen, Bill Price, Gerald Muench, Andrew Shalliker, Vincent Higgins, Dennis Chang, Sabine Piller, Simon Myers, Colin Stack and Michelle Moffitt |
| Funding: |
|
| Title: | Dispersal of rodents and their role in transmission of bacterial pathogens between piggeries |
| Years: | 2008-07-01 - 2008-12-31 |
| ID: | P00016469 |
| UWS Researchers: | Michelle Moffitt and Colin Stack |
| Funding: |
|
Supervision
Doctor Moffitt is available to be a principal supervisor for doctoral projects
Current Supervision
| Title: | Characterisation of Biosynthetic Gene Clusters within Cyanobacteria |
|---|---|
| Field of Research: |