Doctor Michelle Moffitt

Doctor Michelle Moffitt

SENIOR LECTURER,
Medical Science (SoSH)

Personal

Qualifications

  • PhD University of New South Wales
  • BSc University of New South Wales

UWS Organisational Unit (School / Division)

  • Medical Science (SoSH)

Contact

Email:M.Moffitt@uws.edu.au
Extension:3521
Mobile:
Location:21.1.06
Campbelltown
Website:

Publications

Chapters in Books

  • Neilan, B., Pearson, L., Moffitt, M., Kaebernick, M., Mihali, T. and Kellmann, R. (2008), 'The genetics and genomics of cyanobacterial toxicity', Cyanobacterial harmful Algal Blooms: State of the Science and Research Needs, Springer New York 9780387758640.

Journal Articles

  • Cronin, L., Moffitt, M., Mawad, D., Morton, O., Lauto, A. and Stack, C. (2013), 'An in vitro study of the photodynamic effect of rose bengal on Trichophyton rubrum.', Journal of Biophotonics, .
  • Gehringer, M., Adler, L., Roberts, A., Moffitt, M., Mihali, T., Mills, T., Fieker, C. and Neilan, B. (2012), 'Nodularin, a cyanobacterial toxin, is synthesized in planta by symbiotic Nostoc sp.', ISME journal, 14.
  • Pearson, L., Mihali, T., Moffitt, M., Kellmann, R. and Neilan, B. (2010), 'On the Chemistry, Toxicology and Genetics of the Cyanobacterial Toxins, Microcystin, Nodularin, Saxitoxin and Cylindrospermopsin', Marine Drugs, 31.
  • Wiese, M., D'Agostino, P., Mihali, T., Moffitt, M. and Neilan, B. (2010), 'Neurotoxic alkaloids: saxitoxin and its analogs', Marine Drugs, 27.
  • Pearson, L., Moffitt, M., Ginn, H. and Neilan, B. (2008), 'The molecular genetics and regulation of cyanobacterial peptide hepatotoxin biosynthesis', Critical Reviews in Toxicology, 10.
  • Winter, J., Moffitt, M., Zazopoulos, E., Mcalpine, J., Dorrestein, P. and Moore, B. (2007), 'Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster', Journal of Biological Chemistry, 7.
  • Moffitt, M., Louie, G., Bowman, M., Pence, J., Noel, J. and Moore, B. (2007), 'Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization.', Biochemistry-US, 9.
  • Hicks, L., Moffitt, M., Beer, L., Moore, B. and Kelleher, N. (2006), 'Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase', A C S Chemical Biology, 10.
  • Louie, G., Bowman, M., Moffitt, M., Baiga, T., Moore, B. and Noel, J. (2006), 'Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases', Chemistry and Biology, 12.
  • Burns, B., Saker, M., Moffitt, M. and Neilan, B. (2004), 'Molecular detection of genes responsible for cyanobacterial toxin production in the genera Microcystis, Nodularia, and Cylindrospermopsis', Methods in Molecular Biology, 10.
  • Pomati, F., Moffitt, M., Cavaliere, R. and Neilan, B. (2004), 'Evidence for differences in the metabolism of saxitoxin and C1+2 toxins in the freshwater cyanobacterium Cylindrospermopsis raciborskii T3', Biochimica et Biophysica Acta - General subjects, 8.
  • Toh, M., Moffitt, M., Henrichsen, L., Raferty, M., Barrow, K., Cox, J., Marquis, C. and Neilan, B. (2004), 'Cereulide, the emetic toxin of Bacillus cereus, is putatively a product of nonribosomal peptide synthesis', Journal of Applied Microbiology, 9.
  • Moffitt, M. and Neilan, B. (2004), 'Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins', Applied and Environmental Microbiology, 10.
  • Moffitt, M. and Neilan, B. (2003), 'Evolutionary affiliations within the superfamily of ketosynthases reflect complex pathway associations', Journal of Molecular Evolution, 12.
  • Feitz, A., Lukondeh, T., Moffitt, M., Burns, B., Naidoo, D., Della Vedova, J., Gooden, J. and Neilan, B. (2002), 'Absence of detectable levels of the cyanobacterial toxin (microcystin-LR) carry-over into milk', Toxicon, 8.
  • Moffitt, M., Blackburn, S. and Neilan, B. (2001), 'rRNA sequences reflect the ecophysiology and define the toxic cyanobacteria of the genus Nodularia', International Journal of Systematic and Evolutionary Microbiology, 8.
  • Moffitt, M. and Neilan, B. (2001), 'On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia', FEMS Microbiology Letters, 8.

Research

Previous Projects

Title:Natural product genes in cyanobacteria: From microbial genetics to biotechnological applications
Years:2007-12-10 - 2009-06-30
ID:P0015934
UWS Researchers:Michelle Moffitt
Funding:
  • University of Western Sydney
Title:Characterising Genes For The Biosynthesis Of Isoprenoid-Isonitrile Alkaloids In Microorganisms
Years:2006-09-30 - 2007-11-15
ID:P0015261
UWS Researchers:Michelle Moffitt
Funding:
  • University of Western Sydney
Title:Polyketides as the conserved basis for diverse marine toxin biosyntheses [via UNSW]
Years:2008-02-11 - 2011-02-10
ID:P0015529
UWS Researchers:Michelle Moffitt
Funding:
  • Australian Research Council (ACRG)
Title:Establishment of a mass spectrometer facility for natural products and proteomics research and teaching at the College of Health and Science within the University of Western Sydney, Campbelltown campus
Years:2008-09-24 - 2010-09-15
ID:P00016326
UWS Researchers:Nikolaus Sucher, Jens Coorssen, Jens Coorssen, Bill Price, Gerald Muench, Andrew Shalliker, Vincent Higgins, Dennis Chang, Sabine Piller, Simon Myers, Colin Stack and Michelle Moffitt
Funding:
  • University of Western Sydney
Title:Dispersal of rodents and their role in transmission of bacterial pathogens between piggeries
Years:2008-07-01 - 2008-12-31
ID:P00016469
UWS Researchers:Michelle Moffitt and Colin Stack
Funding:
  • Pork CRC Ltd

Supervision

Doctor Moffitt is available to be a principal supervisor for doctoral projects

Current Supervision

Title:Characterisation of Biosynthetic Gene Clusters within Cyanobacteria
Field of Research:

University of Western Sydney

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Penrith NSW 2751

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