
Doctor Michelle Moffitt
SENIOR LECTURER,
Medical Science (SoSH)
Personal
Qualifications
- PhD University of New South Wales
- BSc University of New South Wales
UWS Organisational Unit (School / Division)
- Medical Science (SoSH)
Contact
| Email: | M.Moffitt@uws.edu.au |
|---|---|
| Extension: | 3521 |
| Mobile: | |
| Location: | 21.1.06 Campbelltown |
| Website: |
Publications
Chapters in Books
- Neilan, B., Pearson, L., Moffitt, M., Kaebernick, M., Mihali, T. and Kellmann, R. (2008), 'The genetics and genomics of cyanobacterial toxicity', Cyanobacterial harmful Algal Blooms: State of the Science and Research Needs, Springer New York 9780387758640.
Journal Articles
- Cronin, L., Moffitt, M., Mawad, D., Morton, O., Lauto, A. and Stack, C. (2013), 'An in vitro study of the photodynamic effect of rose bengal on Trichophyton rubrum.', Journal of Biophotonics, .
- Gehringer, M., Adler, L., Roberts, A., Moffitt, M., Mihali, T., Mills, T., Fieker, C. and Neilan, B. (2012), 'Nodularin, a cyanobacterial toxin, is synthesized in planta by symbiotic Nostoc sp.', ISME journal, 14.
- Pearson, L., Mihali, T., Moffitt, M., Kellmann, R. and Neilan, B. (2010), 'On the Chemistry, Toxicology and Genetics of the Cyanobacterial Toxins, Microcystin, Nodularin, Saxitoxin and Cylindrospermopsin', Marine Drugs, 31.
- Wiese, M., D'Agostino, P., Mihali, T., Moffitt, M. and Neilan, B. (2010), 'Neurotoxic alkaloids: saxitoxin and its analogs', Marine Drugs, 27.
- Pearson, L., Moffitt, M., Ginn, H. and Neilan, B. (2008), 'The molecular genetics and regulation of cyanobacterial peptide hepatotoxin biosynthesis', Critical Reviews in Toxicology, 10.
- Winter, J., Moffitt, M., Zazopoulos, E., Mcalpine, J., Dorrestein, P. and Moore, B. (2007), 'Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster', Journal of Biological Chemistry, 7.
- Moffitt, M., Louie, G., Bowman, M., Pence, J., Noel, J. and Moore, B. (2007), 'Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization.', Biochemistry-US, 9.
- Hicks, L., Moffitt, M., Beer, L., Moore, B. and Kelleher, N. (2006), 'Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase', A C S Chemical Biology, 10.
- Louie, G., Bowman, M., Moffitt, M., Baiga, T., Moore, B. and Noel, J. (2006), 'Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases', Chemistry and Biology, 12.
- Burns, B., Saker, M., Moffitt, M. and Neilan, B. (2004), 'Molecular detection of genes responsible for cyanobacterial toxin production in the genera Microcystis, Nodularia, and Cylindrospermopsis', Methods in Molecular Biology, 10.
- Pomati, F., Moffitt, M., Cavaliere, R. and Neilan, B. (2004), 'Evidence for differences in the metabolism of saxitoxin and C1+2 toxins in the freshwater cyanobacterium Cylindrospermopsis raciborskii T3', Biochimica et Biophysica Acta - General subjects, 8.
- Toh, M., Moffitt, M., Henrichsen, L., Raferty, M., Barrow, K., Cox, J., Marquis, C. and Neilan, B. (2004), 'Cereulide, the emetic toxin of Bacillus cereus, is putatively a product of nonribosomal peptide synthesis', Journal of Applied Microbiology, 9.
- Moffitt, M. and Neilan, B. (2004), 'Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins', Applied and Environmental Microbiology, 10.
- Moffitt, M. and Neilan, B. (2003), 'Evolutionary affiliations within the superfamily of ketosynthases reflect complex pathway associations', Journal of Molecular Evolution, 12.
- Feitz, A., Lukondeh, T., Moffitt, M., Burns, B., Naidoo, D., Della Vedova, J., Gooden, J. and Neilan, B. (2002), 'Absence of detectable levels of the cyanobacterial toxin (microcystin-LR) carry-over into milk', Toxicon, 8.
- Moffitt, M., Blackburn, S. and Neilan, B. (2001), 'rRNA sequences reflect the ecophysiology and define the toxic cyanobacteria of the genus Nodularia', International Journal of Systematic and Evolutionary Microbiology, 8.
- Moffitt, M. and Neilan, B. (2001), 'On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia', FEMS Microbiology Letters, 8.
Research
Previous Projects
| Title: | Natural product genes in cyanobacteria: From microbial genetics to biotechnological applications |
|---|---|
| Years: | 2007-12-10 - 2009-06-30 |
| ID: | P0015934 |
| UWS Researchers: | Michelle Moffitt |
| Funding: |
|
| Title: | Characterising Genes For The Biosynthesis Of Isoprenoid-Isonitrile Alkaloids In Microorganisms |
| Years: | 2006-09-30 - 2007-11-15 |
| ID: | P0015261 |
| UWS Researchers: | Michelle Moffitt |
| Funding: |
|
| Title: | Polyketides as the conserved basis for diverse marine toxin biosyntheses [via UNSW] |
| Years: | 2008-02-11 - 2011-02-10 |
| ID: | P0015529 |
| UWS Researchers: | Michelle Moffitt |
| Funding: |
|
| Title: | Establishment of a mass spectrometer facility for natural products and proteomics research and teaching at the College of Health and Science within the University of Western Sydney, Campbelltown campus |
| Years: | 2008-09-24 - 2010-09-15 |
| ID: | P00016326 |
| UWS Researchers: | Nikolaus Sucher, Jens Coorssen, Jens Coorssen, Bill Price, Gerald Muench, Andrew Shalliker, Vincent Higgins, Dennis Chang, Sabine Piller, Simon Myers, Colin Stack and Michelle Moffitt |
| Funding: |
|
| Title: | Dispersal of rodents and their role in transmission of bacterial pathogens between piggeries |
| Years: | 2008-07-01 - 2008-12-31 |
| ID: | P00016469 |
| UWS Researchers: | Michelle Moffitt and Colin Stack |
| Funding: |
|
Supervision
Doctor Moffitt is available to be a principal supervisor for doctoral projects
Current Supervision
| Title: | Characterisation of Biosynthetic Gene Clusters within Cyanobacteria |
|---|---|
| Field of Research: |