Professor Kelvin Chan

Professor Kelvin Chan

JOINT CHAIR IN TRAD CHINESE MEDICINE,
Centre for Complementary Medicine Research

Personal

Qualifications

  • DSc University of Birmingham (UK)
  • PhD University of Birmingham (UK)
  • Master of Science Aston University (UK)
  • BSc (Pharm) Liverpool Regional College of Technology

UWS Organisational Unit (School / Division)

  • Centre for Complementary Medicine Research

Contact

Email:JCTCM@uws.edu.au
Extension:3837
Mobile:0410725842
Location:22.1.17
Campbelltown
Website:

Biography

Professor Kelvin Chan holds the position of Professor - Joint Chair in Traditional Chinese Medicine at CompleMED, UWS,  and the Herbal Medicine Research & Education Centre, University of Sydney.

Professor Chan is a Charted Biologist (UK), Clinical Pharmacologist (UK and USA) and Registered Pharmacist (UK). He is a Fellow of the following academic institutes: Royal Pharmaceutical Society of Great Britain; the Society of Biology, UK; the Royal Society of Medicine, UK and the American College of Clinical Pharmacology, USA.

Formerly, he was Founding Chair Professor in Pharmacy & Pharmacology, Head and then Director of Pharmacy & Pharmaceutical Sciences at University of Wolverhampton, UK (2005 to 2009); Chair Professor of Biomedical Sciences and Director of R&D at the Institute for the Advancement of Chinese Medicine, Hong Kong Baptist University (2000 - 2005) and Chair Professor of Biomedical Science and Research Director of the School of Pharmacy at the Liverpool Johns Moores University. He held Visiting Professorships at the University of Liverpool and Middlesex University in the UK; Institute of Pharmacognosy & Pharmacy, University of Vienna, Austria; Pharmaceutical University in Nanjing and Shenyang Pharmaceutical University in Shenyang in PR China. He is currently Visiting Professor at the Institute of Medicinal Plant Development in Beijing and JiNan University in Guangzhou, PR China as well as at the University of Wolverhampton, UK.

Professor Chan's has over 220 peer-reviewed full papers, and those published from the ealry 1990s are mainly related to  mechanistic studies of interactions between herbal medicines and pharmaceuticals. His research directions and interests have since changed towards medicinal and pharmaceutical development of Chinese herbal medicines and natural products.

This information has been contributed by Professor Chan.

Awards

  • Life Fellow, Travel awarded by the Winston Churchill Memorial Trust, UK on a fact finding mission: 1995-12-01
  • British Pharmaceutical Conference Sciences Awards, RPSGB, UK 1983-12-01

Publications

Chapters in Books

  • Li , G., Wong , K., Kam, A., Zhou , X., Omar , E., Alqahtani , A., Li, K., Razmovski-Naumovski, V. and Chan, K. (2012), 'Anti-inflammatory nutraceuticals and herbal medicines for the management of metabolic syndrome', Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions, CRC Press 9781439872116.
  • Li, G., Kam, A., Wong, K., Zhou, X., Omar, E., Alqahtani, A., Li, K., Razmovski-Naumovski, V. and Chan, K. (2012), 'Herbal medicines for the management of diabetes ', Diabetes : an Old Disease, a New Insight, Springer 9781461454403.
  • Chan, K., Zhang, H. and Lin, Z. (2011), 'Treatments used in complementary and alternative medicine', Side Effects of Drugs Annual (SEDA): 33, Elsevier 9780444537416.
  • Chan, K. and Lin, Z. (2010), 'Treatments used in complementary and alternative medicine', Side Effects of Drugs - Annual 32, Elsevier 9780444535504.

Journal Articles

  • Lu, A., Chan, K., Jiang, M., Zhang, C., Zhang, C. and Chan, K. (2012), 'An integrative approach of linking traditional Chinese medicine pattern classification and biomedicine diagnosis', Journal of Ethnopharmacology, 8.
  • Lu, A., Chan, K., Jiang, M., Zhang, C., Zhang, C. and Chan, K. (2012), 'An integrative approach of linking traditional Chinese medicine pattern classification and biomedicine diagnosis', Journal of Ethnopharmacology, 8.
  • Chan, K., Chua, M., Chan, K., Hocking, T., Williams, P., Perry, C. and Baldwin, T. (2012), 'Methodologies for the extraction and analysis of konjac glucomannan from corms of Amorphophallus konjac K. Koch.', Carbohydrate Polymers, 9.
  • Chan, K., Chua, M., Chan, K., Hocking, T., Williams, P., Perry, C. and Baldwin, T. (2012), 'Methodologies for the extraction and analysis of konjac glucomannan from corms of Amorphophallus konjac K. Koch.', Carbohydrate Polymers, 9.
  • Kam, A., Li, K., Naumovski, V., Nammi, S., Chan, K., Li, Y. and Li, G. (2012), 'The protective effects of natural products on blood-brain barrier breakdown', Current Medicinal Chemistry, 16.
  • Qu, F., Zhou, J., Bovey, M., Franconi, G., Chan, K., Smith, C., Jiang, D. and Robinson, N. (2012), 'Does acupuncture improve the outcome of in vitro fertilisation? Guidance for future trials', European Journal of Integrative Medicine, 11.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2012), 'Combination of TNF-a, homocysteine and adenosine exacerbated cytotoxicity in human cardiovascular and cerebrovascular endothelial cells', Cellular Physiology and Biochemistry, 10.
  • Chua, M., Chan, K., Hocking, T., Williams, P., Perry, C. and Baldwin, T. (2012), 'Methodologies for the extraction and analysis of konjac glucomannan from corms of Amorphophallus konjac K. Koch', Carbohydrate Polymers, 9.
  • Lu, A., Jiang, M., Zhang, C. and Chan, K. (2012), 'An integrative approach of linking traditional Chinese medicine pattern classification and biomedicine diagnosis', Journal of Ethnopharmacology, 8.
  • Qu, F., Zhou, J., Bovey, M., Franconi, G., Chan, K., Smith, C., Jiang, D. and Robinson, N. (2012), 'Does acupuncture improve the outcome of in vitro fertilisation? Guidance for future trials', European Journal of Integrative Medicine, 11.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Nammi, S., Chan, K. and Li, G. (2012), 'Combination of TNF-a, homocysteine and adenosine exacerbated cytotoxicity in human cardiovascular and cerebrovascular endothelial cells', Cellular Physiology and Biochemistry, 10.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K., Li, Y. and Li, G. (2012), 'The protective effects of natural products on blood-brain barrier breakdown', Current Medicinal Chemistry, 16.
  • Fan , T., Shikov , A., Kim , Y., Huang , Y., Chang , Y., Jia , W., Dias , A., Wong , V., Chan, K., Deal , G., Koo , H., Rees , D., Sun , H., Chen , S., Dou , J., Makarov , V. and Pozharitskaya, O. (2012), 'Future development of global regulations of Chinese herbal products', Journal of Ethnopharmacology, 19.
  • Zhang, L., Yan, J., Liu, X., Ye, Z., Yang, X., Meyboom, R., Chan, K., Shaw, D. and Duez, P. (2012), 'Pharmacovigilance practice and risk control of Traditional Chinese Medicine drugs in China : current status and future perspective', Journal of Ethnopharmacology, 7.
  • Pelkonen, O., Pasanen, M., Lindon, J., Chan, K., Zhao, L., Deal, G., Xu, Q. and Fan, T. (2012), 'Omics and its potential impact on R&D and regulation of complex herbal products', Journal of Ethnopharmacology, 7.
  • Jiang , M., Lu , C., Zhang, C., Yang , J., Tan, Y., Lu, A. and Chan, K. (2012), 'Syndrome differentiation in modern research of traditional Chinese medicine', Journal of Ethnopharmacology, 9.
  • Ouedraogo, M., Shaw, D., Pelkonen, O., Duez, P., Baudoux, T., Stevigny, C., Nortier, J., Colet, J., Efferth, T., Qu, F., Zhou, J. and Chan, K. (2012), 'Review of current and 'omics' methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms', Journal of Ethnopharmacology, 21.
  • Shaw, D., Ladds, G., Duez, P., Williamson, E. and Chan, K. (2012), 'Pharmacovigilance of herbal medicine', Journal of Ethnopharmacology, 6.
  • Chan, K., Verpoorte, R., Williamson, E., Duez, P., Shaw, D., Simmonds, M., Leon, C., Xu, Q., Lu, A., Sutherland, I., Ignatova, S. and Zhu, Y. (2012), 'Good practice in reviewing and publishing studies on herbal medicine, with special emphasis on traditional Chinese medicine and Chinese materia medica', Journal of Ethnopharmacology, 7.
  • Hung, M., Zhang, Z., Li, S., Lei, B., Yuan, S., Cui, G., Hoi, P., Chan, K. and Lee, S. (2012), 'From omics to drug metabolism and high content screen of natural product in zebrafish : a new model for discovery of neuroactive compound', Evidence-Based Complementary and Alternative Medicine, 18.
  • Zhou, X., Chan, K. and Yeung, J. (2012), 'Herb-drug interactions with Danshen (Salvia miltiorrhiza) : a review on the role of cytochrome P450 enzymes', Drug Metabolism and Drug Interactions, 10.
  • Yeh, J., Ziche, M., Charnock-Jones, D., Fan, T., Cindrova-Davis, T., Belleri, M., Morbidelli, L., Miller, N., Cho, C., Chan, K., Wang, Y. and Luo, G. (2011), 'The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinesis inhibits angiogenesis in vitro and in vivo', Journal of Angiogenesis Research, 11.
  • Chan, K., Jiang, M., Zhang, C., Cao, H., Chan, K., Cao, H. and Lu, A. (2011), 'The role of Cinese medicine in the treatment of chronic diseases in China', Planta Medica, 9.
  • Chan, K., Jiang, M., Zhang, C., Cao, H., Chan, K., Cao, H. and Lu, A. (2011), 'The role of Cinese medicine in the treatment of chronic diseases in China', Planta Medica, 9.
  • Poon, S., Chan, K., Chan, K., Sze, D., Poon, J., Mcgrane, M., Zhou, X., Kwan, P., Zhang, R., Liu, B., Gao, J. and Loy, C. (2011), 'A novel approach in discovering significant interactions from TCM patient prescription data', International Journal of Data Mining and Bioinformatics, 16.
  • Poon, S., Chan, K., Chan, K., Sze, D., Poon, J., Mcgrane, M., Zhou, X., Kwan, P., Zhang, R., Liu, B., Gao, J. and Loy, C. (2011), 'A novel approach in discovering significant interactions from TCM patient prescription data', International Journal of Data Mining and Bioinformatics, 16.
  • Wong, K., Chan, K., Naumovski, V., Li, G., Li, K., Naumovski, V., Li, G., Chan, K. and Wong, K. (2011), 'Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases', Journal of Ethnopharmacology, 21.
  • Wong, K., Chan, K., Naumovski, V., Li, G., Li, K., Naumovski, V., Li, G., Chan, K. and Wong, K. (2011), 'Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases', Journal of Ethnopharmacology, 21.
  • Jiang, M., Zhang, C., Cao, H., Chan, K. and Lu, A. (2011), 'The role of Chinese medicine in the treatment of chronic diseases in China.', Planta Medica, 9.
  • Wong, K., Li, G., Li, K., Naumovski, V. and Chan, K. (2010), 'Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases', Journal of Ethnopharmacology, 24.
  • Omar, E., Kam, A., Alqahtani, A., Li, K., Naumovski, V., Nammi, S., Chan, K., Roufogalis, B. and Li, G. (2010), 'Herbal medicines and nutraceuticals for diabetic vascular complications: mechanisms of action and bioactive phytochemicals', Current Pharmaceutical Design, 32.
  • Zhao, Z., Liang, Z., Chan, K., Lu, G., Lee, E., Chen, H. and Li, L. (2010), 'A unique issue in the standardization of Chinese materia medica: Processing', Planta Medica, .
  • Jiang, M., Yang, J., Zhang, C., Liu, B., Chan, K., Cao, H. and Lu, A. (2010), 'Clinical studies with traditional Chinese medicine in the past decade and future research and development', Planta Medica, .
  • Liang, Y., Xie, P. and Chan, K. (2010), 'Perspective of chemical fingerprinting of Chinese herbs', Planta Medica, .
  • Sun, S., Chen, J., Zhou, Q., Lu, G. and Chan, K. (2010), 'Application of Mid-infrared spectroscopy in the quality control of traditional Chinese medicines', Planta Medica, .
  • Singh, S., Singh, V., Kar, N. and Chan, K. (2010), 'Efficacy of antidepressants in negative symptoms of chronic schizophrenia: systematic review and meta-analysis', British Journal of Psychiatry, 6.
  • Chua, M., Baldwin, T., Hocking, T. and Chan, K. (2010), 'Traditional uses and potential health benefits of Amorphophallus konjac K.Koch ex N.E.Br', Journal of Ethnopharmacology, 11.
  • Chui, S., Shek, S., Fong, M., Szeto, Y. and Chan, K. (2010), 'A panel study to assess the quality of life assessments in patients suffering from allergic rhinitis after treatment with a Chinese herbal nasal drop', Phytotherapy Research, 5.
  • Liang, Y., Xie, P. and Chan, K. (2010), 'Chromatographic fingerprinting and metabolomics for quality control of TCM', Combinatorial Chemistry and High Throughput Screening, 11.
  • Singh, V., Singh, S. and Chan, K. (2009), 'Review and meta-analysis of usage of Ginkgo as an adjunct therapy in chronic schizophrenia', The International Journal of Neuropsychopharmacology, 15.
  • Chan, K., Leung, K. and Zhao, S. (2009), 'Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials', Chinese Medicine, .
  • Wang, J., Van Der Heijden, R., Spruit, S., Hankermeier, T., Chan, K., Van Der Greef, J., Xu, G. and Wang, M. (2009), 'Quality and safety of Chinese medicine herbal medicines guided by a systems biology perspective', Journal of Ethnopharmacology, 11.
  • Yu, H., Li, W., Cheung, M., Zuo, Z., Carlier, P., Gu, Z., Chan, K. and Huang, M. (2009), 'Development and validation of an HPLC-DAD method for bis(12)-hupyridone and its application to a pharmacokinetic study', Journal of Pharmaceutical and Biomedical Analysis, 5.
  • Lee, N., Nehmeh, S., Schoder, H., Fury, M., Chan, K., Ling, C. and Humm, J. (2009), 'Prospective Trial Incorporating Pre-/Mid-Treatment [18F]-Misonidazole Positron Emission Tomography for Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy', International Journal of Radiation Oncology Biology Physics, 8.
  • Zhao, L., Leung, K., Liu, F., Chen, J. and Chan, K. (2008), 'Responsiveness of the Chinese quality of Life Instrument in patients with congestive heart failure', Chinese Journal of Integrative Medicine, 7.
  • Cui, L., Chan, W., Wu, J., Jiang, Z., Chan, K. and Cai, Z. (2008), 'High performance liquid chromatography-mass spectrometry analysis for rat metabolism and pharmacokinetic studies of lithospermic acid B from danshen', Talanta, 6.
  • Chui, S., Chow, F., Chan, K., Fu, S. and Szeto, Y. (2008), 'Slimpid may boost plasma IGF-1 level and improve the quality of life in patients with risk of developing metabolic syndrome', Journal of Complementary and Integrative Medicine, .
  • Chan, K. (2008), 'An overview on safety issues of interactions between traditional herbal medicines and pharmaceutical medicines', Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 20.
  • Yu, H., Han, Y., Kan, K., Ho, J., Li, W., Carlier, P., Pang, Y., Gu, Z., Chan, K. and Wang, Y. (2008), 'The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine', Journal of Pharmaceutical and Biomedical Analysis, 7.
  • Zhang, L., Han, Y., Yu, H., Li, W., Cheung, M., Pang, Y., Gu, Z., Chan, K., Wang, Y. and Zuo, Z. (2008), 'Preclinical characterization of intestinal absorption and metabolism of promising anti-Alzheimer's dimer bis(7)-tacrine', International Journal of Pharmaceutics, 10.
  • Leung, K., Chan, K., Bensoussan, A. and Munroe, M. (2007), 'Application of atmospheric pressure chemical ionisation mass spectrometry in the identification and differentiation of the Panax species', Phytochemical Analysis, 5.
  • Yu, H., Li, W., Kan, K., Chan, K., Wang, Y. and Han, Y. (2007), 'An overview on the progress of pharmacokinetics of anti-Alzheimer drugs', Chinese Pharmaceutical Journal, 5.
  • Tin, M., Cho, C., Chan, K., James, A. and Ko, J. (2007), 'Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft', Carcinogenesis, 9.
  • Yi, T., Leung, K., Lu, G., Zhang, H. and Chan, K. (2007), 'Identification and determination of the major constituents in traditional Chinese medicinal plant polygonum multiflorum Thunb by HPLC coupled with PAD and ESI/MS', Phytochemical Analysis, 7.
  • Lu, G., Cheng, S., Leung, K., Ma, J., Chan, K. and Zhao, Z. (2007), 'Determination of free and total available ferulic acid in different types of Chinese Angelica by high performance liquid chromatography', Journal of Food and Drug Analysis, 9.
  • Zhao, L., Leung, K. and Chan, K. (2007), 'The Chinese quality of life instrument: Reliability and validity of the Hong Kong Chinese version (ChQOL-HK)', Hong Kong Practitioner, 13.
  • Yu, H., Wang, Y., Han, Y., Ho, J., Kan, K., Cheng, B., Li, W., Lin, G., Pang, Y., Gu, Z. and Chan, K. (2007), 'Development of a high performance liquid chromatography-tandem mass method for determination of bis(7)-tacrine, a promising anti-Alzheimer's dimer, in rat blood', Journal of Pharmaceutical and Biomedical Analysis, 6.
  • Liu, H., Sun, S., Lu, G. and Chan, K. (2006), 'Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy', Spectrochimica acta part A, 6.
  • Qing, L., Zhang, H., Lu, G., Chan, K., Leung, K. and Chen, C. (2006), 'Determination of oleanolic acid in Caulis Clematidis armadii by HPLC', West China Journal of Pharmacy Science, 2.
  • Yi, T., Leung, K., Lu, G., Chan, K. and Zhang, H. (2006), 'Simultaneous qualitative and quantitative analyses of the major constituents in the rhizome of Ligusticum chuanxiong using HPLC-DAD-MS', Chemical and Pharmaceutical Bulletin, 5.
  • Fang, K., Liang, Y., Yin, X., Chan, K. and Lu, G. (2006), 'Critical value determination on similarity of fingerprints', Chemometrics and Intelligent Laboratory Systems, 5.
  • Chan, K., Liu, Z., Jiang, Z., Zhou, H., Wong, Y., Xu, H. and Liu, L. (2006), 'The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model', Journal of Ethnopharmacology, 8.
  • Ha, W., Lau, C., Yue, P., Hung, K., Chan, K., Chui, S., Chui, A., Yam, W. and Wong, R. (2006), 'Simultaneous detection of precore/basal core promoter mutations in hepatitis B virus using arrayed primer extension', Molecular Diagnosis and Therapy, 10.
  • Cheung, T., Xue, C., Leung, K., Chan, K. and Li, C. (2006), 'Aristolochic acids detected in some raw Chinese medicinal herbs and manufactured herbal products - A consequence of inappropriate nomenclature and imprecise labelling?', Clinical Toxicology, 8.
  • Zhao, L., Liu, F., Leung, K., Chan, K. and Fang, J. (2006), 'Reliability and validity of the Chinese Quality of Life Instrument', Chinese Journal of Clinical Rehabilitation, 3.
  • Leung, K., Cheng, Y., Mak, N., Chan, K., David Fan, T. and Wong, R. (2006), 'Signaling pathway of ginsenoside-Rg1 leading to nitric oxide production in endothelial cells', FEBS Letters, 6.
  • Zhao, L., Chan, K., Leung, K., Liu, F., Lang, J. and Fang, J. (2005), 'The Chinese quality of life instrument: Development of a new health-related quality of life using factor analysis and structural equation modelling', Journal of Complementary and Integrative Medicine, 22.
  • Zhao, L., Chan, K., Leung, K., Liu, F. and Fang, J. (2005), 'The conceptual structure of the Chinese Quality of Life (ChQOL) Instrument', Annals of Traditional Chinese Medicine, Chinese Medicine - Modern Practice, 9.
  • Yi, T., Leung, K., Lu, G., Zhang, H. and Chan, K. (2005), 'Identification and comparative determination of senkyunolide A in traditional Chinese medicinal plants Ligusticum chuanxiong and Angelica sinensis by HPLC coupled with DAD and ESI-MS', Chemical and Pharmaceutical Bulletin, 4.
  • Lu, G., Chan, K., Leung, K., Chan, C., Zhao, Z. and Jiang, Z. (2005), 'Assay of free ferulic acid and total ferulic acid for quality assessment of Angelica sinensis', Journal of Chromatography A, 11.
  • Liu, Z., Chan, K., Zhou, H., Jiang, Z., Wong, Y., Xu, H. and Liu, L. (2005), 'The pharmacokinetics and tissue distribution of sinomenine in rats and its protein binding ability in vitro', Life Sciences, 13.
  • Liu, Z., Zhou, H., Liu, L., Jiang, Z., Wong, Y., Xie, Y., Cai, X., Xu, H. and Chan, K. (2005), 'Influence of co-administrated sinomenine on pharmacokinetic fate of paeoniflorin in unrestrained conscious rats', Journal of Ethnopharmacology, 7.
  • Leung, K., Chan, K., Lau, A. and Lu, G. (2005), 'Measurement uncertainty for total ash and acid-insoluble ash determination of Chinese materia medica', Accreditation and Quality Assurance, 6.
  • Yue, P., Fan, T., Wong, R., Wong, D., Ha, W., Fung, M., Mak, N., Yeung, H., Leung, H., Chan, K. and Liu, L. (2005), 'Elucidation of the mechanisms underlying the angiogenic effects of ginsenoside Rg1 in vivo and in vitro', Angiogenesis, 12.
  • Zhong, Q., Zhi, H., Chan, K., Zhou, H., Yuen, F., Zhao, X., Hong, X. and Liu, L. (2005), 'Pharmacokinetic interaction of paeoniflorin and sinomenine: Pharmacokinetic parameters and tissue distribution characteristics in rats and protein binding ability in vitro', Journal of Pharmacological Sciences, 11.
  • Leung, K., Liu, F., Zhao, L., Fang, J., Chan, K. and Lin, L. (2005), 'Development and validation of the Chinese Quality of Life Instrument', Health and Quality of Life Outcomes, .
  • Zhao, L. and Chan, K. (2005), 'Building a bridge for integrating Chinese medicine into conventional healthcare: Observations drawn from the development of the Chinese quality of life instrument', American Journal of Chinese Medicine, 6.
  • Lu, G., Chan, K., Laing, Y., Leung, K., Chan, C., Jian, Z. and Zhao, Z. (2005), 'Development of high-performance liquid chromatographic fingerprints for distinguishing Chinese Angelica from related umbelliferae herbs', Journal of Chromatography A, 10.
  • Chui, S., Chan, K., Chui, A., Shek, L. and Wong, R. (2005), 'The effects of a Chinese medicinal suppository (Vitalliver) on insulin-like growth factor 1 and homocysteine in patients with hepatitis B infection', Phytotherapy Research, 5.
  • Leung, K., Chan, K., Chan, C. and Lu, G. (2005), 'Systematic evaluation of organochlorine pesticide residues in Chinese materia medica', Phytotherapy Research, 5.
  • Leung, K. and Chan, K. (2004), 'Regulatory System of Proprietary Chinese Medicine in Hong Kong', Journal of Complementary and Integrative Medicine, .
  • Zhao, L., Liu, F., Leung, K., Fang, J., Lin, L. and Chan, K. (2004), 'Discussion on the theory and structure model of the Chinese quality of life instrument', Chinese Journal of Clinical Rehabilitation, 3.
  • Liu, F., Zhao, L., Leung, K., Fang, J., Lin, L. and Chan, K. (2004), 'Discussing the probability and steps of setting up the system of instruments used for assessment of clinical effectiveness of traditional Chinese medicine', Chinese Journal of Clinical Rehabilitation, 2.
  • Zhao, L., Chan, K., Leung, K., Liu, F. and Fang, J. (2004), 'Application of factor analysis in development and validation of a new questionnaire for quality of life', Chinese Journal of Integrated Traditional and Western Medicine, 4.
  • Lu, G., Chan, K., Chan, C., Leung, K., Jiang, Z. and Zhao, Z. (2004), 'Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry', Journal of Chromatography A, 7.
  • Chui, S., Chan, K., Wong, R. and Chen, K. (2004), 'A panel study on the effects of a Chinese medicinal suppository, Vigconic VI-28, on insulin-like growth factor 1 and homocysteine in healthy men', Methods and Findings in Experimental and Clinical Pharmacology, 7.
  • Chan, K., Chui, S., Wong, D., Ha, W., Chan, C. and Wong, R. (2004), 'Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine induced endothelial dysfunction', Life Sciences, 15.
  • Hu, S., Zhang, H., Chan, K. and Mei, Q. (2004), 'Studies on the toxicity of Aristolochia manshuriensis (Guanmuton)', Toxicology, 7.
  • Lu, G., Sun, S., Leung, H. and Chan, K. (2004), 'Study on the identification of Dangguitou and Dangguiwei by Two-Dimensional infrared correlation spectroscopy', Spectroscopy and Spectral Analysis, 4.
  • Hu, S., Zhang, H., Chan, K. and Mei, Q. (2003), 'Preliminary studies on the toxicity of Guang Fang Ji', Zhong Yao Cai (Chinese Materia Medica), 4.
  • Zhao, L. and Chan, K. (2003), 'The health concept in Chinese medicine', Medicine and Philosophy, 2.
  • Zhao, L. and Chan, K. (2003), 'Quality of life assessment: An outcome estimation of Chinese medical treatment', Chinese Journal of Integrative Medicine, 3.
  • Di, X., Chan, K., Leung, H. and Huie, C. (2003), 'Fingerprint profiling of acid hydrolyzates of polysaccharide extracted from the fruiting bodies and spores of Lingzhi by high-performance thin-layer chromatography', Journal Chromatography A, 11.
  • Choi, M., Chan, K., Leung, H. and Chiu, C. (2003), 'Pressurised liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions', Journal Chromatography A, 10.
  • Song, Z., Bi, K., Luo, X. and Chan, K. (2002), 'The isolation, identification and determination of dehydrotumulosic acid in Poria cocos', Analytical Sciences, 3.
  • Liu, X., Zakaria, M., Islam, M., Radhakrishnan, R., Ismail, A., Chen, H., Chan, K. and Al-Attas, A. (2001), 'Anti-inflammatory and anti-ulcer activity of Calligonum comosum in rats', Fitoterapia, 5.
  • Zakaria, M., Islam, M., Radhakrishnana, R., Chen, H., Kamil, M., Al-gifri, M., Chan, K. and Al-Attas, A. (2001), 'Anti-nociceptive and anti-inflammatory properties of Caralluma Arabica', Journal of Ethnopharmacology, 4.
  • Radhakrishnan, R., Zakaria, M., Islam, M., Chen, H., Kamil, M., Chan, K. and Al-Attas, A. (2001), 'Neuropharmacological actions of Portulaca oleraceae L v. sativa (Hawk)', Journal of Ethnopharmacology, 6.
  • Chan, K. (2001), 'Generating fingerprinting from analytical techniques alone is not enough in the assurance for quality, efficacy and safety of Chinese medicinal herbs and herbal products.', Analytical Sciences, 4.

Conference Papers

  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2012), 'Protective effects of pomegranate peel against endothelial cell death caused by homocysteine, adenosine and TNF-alpha', Consortium for Globalization of Chinese Medicine (CGCM), Macau.
  • Kam, A., Li, K., Razmovski-Naumovski, V., Nammi, S., Chan, K. and Li, G. (2012), 'Intercontinental Variability in the Polyphenolic Profile and Total Antioxidant Capacity of Pomegranate Peel', 11th Annual Oxford International Conference on the Science of Botanicals (ICBS), Oxford, Mississippi.
  • Chua, M., Hocking, T., Baldwin, T. and Chan, K. (2008), 'The analysis and composition of glucomannans from corms of the Chinese medicinal herb Amorphophallus konjac', Meeting of the Society of Environmental Biology, Marseilles.
  • Chan, K. (2008), 'Quality and safety of traditional Chinese medicines and their interactions with pharmaceuticals', Clinical Pharmacology Workshop on Evidence Based Medicine and the Rational Use of Drugs, Zagreb.
  • Chan, K. (2008), 'A Feasible Approach for Assessing Efficacy & Safety of Herbal Products from Composite Mixtures of Medicinal Materials', The 3rd International Congress on Complementary Medicine Research, Sydney.
  • Chan, K. (2008), 'Screening of Bioactivities & Clinical Studies of Medicinal Plants', The 22nd Malaysian Society of Pharmacology & Physiology, Kuala Lumpur.
  • Perry, C., Chan, K., Fuller, K. and Guerra, T. (2008), 'Progress on buriti oil project: A report', 6th Concertation meeting of BORASSUS project, Thailand.
  • Chow, F., Chan, K., Leung, K., Cheng, S. and Zhao, Z. (2007), 'Ferulic acid assay and its relevant use in quality assurance of medicinal herbs', British Pharmaceutical Conference, Manchester UK.
  • Chow, F., Chan, K., Fu, S. and Chui, S. (2007), 'Effect of Slimpid on the quality of life and plasma IGF-1 level in patients with risk of metabolic syndrome Effect of Slimpid on the quality of life and plasma IGF-1 level in patients with risk of metabolic syndrome', Annual Conference of the Chinese Medicial Institute & Register on Integrative Medicine-Direction & Healthcare System, London UK.
  • Chan, K. (2006), 'GAP, Method Development for QC & Clinical Studies of Herbal Medicinal Products', 12th Asian Symposium on Medicinal Plants, Spices and other Natural Products (ASOMPS XII) , Padang, Indonesia.
  • Lu, G., Chan, K., Leung, K., Zhao, Z., Su, C. and Liu, X. (2006), 'Compartive assessment of the processing methods for Radix Angelicae Sinensis (Danggui)', British Pharmaceutical Conference, Manchester UK.
  • Chan, K. (2005), 'Effects of Chinese Medicinal Suppository (Vitalliver) on insulin-like growth factor-1 and homocysteine in chronic hepatitis B carriers', Inaugural international congress on complementary and alternative medicines (ICCAM), Singapore.

Research

Current Projects

Title:Pharmacological interactions of Oncozac (Coriolus versicolor,Yunzhi) and chemotherapy medictions
Years:2012-06-20 - 2013-06-19
ID:P00020998
UWS Researchers:Kelvin Chan, Valentina Naumovski and Srinivas Nammi
Funding:
  • University of Western Sydney
  • PuraPharm Australia Pty Ltd
Title:Synergistic activity of herbal medicines in stroke
Years:2012-11-15 - 2013-12-15
ID:P00021202
UWS Researchers:Kelvin Chan and Valentina Naumovski
Funding:
  • University of Western Sydney
Title:Strengthening Australia - China cooperation in research on plants for use in traditional Chinese medicine
Years:2012-06-01 - 2013-07-31
ID:P00020857
UWS Researchers:Kelvin Chan, Alan Bensoussan and David Briggs
Funding:
  • Department of Industry, Innovation, Climate Change, Science, Research and Tertiary Education (ACRG)
Title:Naoxinqing Pian Research Program Phase I
Years:2011-10-21 - 2013-12-30
ID:P00020675
UWS Researchers:Dennis Chang, Kelvin Chan and Alan Bensoussan
Funding:
  • Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co. Ltd

Previous Projects

Title:Traditional Medicine Internationalisation Platform
Years:2011-06-30 - 2012-12-31
ID:P00020056
UWS Researchers:Alan Bensoussan, Kelvin Chan and Dennis Chang
Funding:
  • University of Western Sydney
  • Department of Industry and Investment NSW

Supervision

Current Supervision

Title:Mechanistic Studies of Two-Herb Combination for Vascular Disease
Field of Research:

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